PRODUCT DESCRIPTION
EPA DHA and Heart health
Clinical and Epidemiological evidence suggests that EPA and DHA help reduce risk factors for heart disease, including high cholesterol and high blood pressure. EPA / DHA has been shown to lower levels of triglycerides, and to lower the risk of death, heart attack, stroke, and abnormal heart rhythms in people who have already had a heart attack EPA / DHA also appear to help prevent and treat atherosclerosis by slowing the development of plaques and blood clots.(1,2)
Scientific reviews conclude that focusing on the combined consumption of EPA and DHA (given the potential for complementary effects) is the best strategy to improve heart health (13). EPA and DHA are thought to have anti-inflammatory effects and a role in oxidative stress (14) and to improve cellular function through changes in gene expression (15). Circulating markers of inflammation, such as C-reactive protein (CRP),
TNFα, and some ILs (IL-6, IL-1), correlate with an increased probability of experiencing a cardiovascular event (16)
Vit D and Heart health
An estimated 1 billion people in the world have vitamin D deficiency or insufficiency, and undiagnosed vitamin D deficiency is common.
Vitamin-D-related pathways are implicated in various endocrine, inflammatory and endothelial functions. Vitamin D deficiency is associated with substantial increases in the incidence of hypertension, hyperlipidaemia, myocardial infarction and stroke. Lowvitamin D levels also up-regulate the renin-angiotensin-aldosterone system, increase inflammation and cause endothelial dysfunction (17). Additionally, vitamin D deficiency causes an increase in parathyroid hormone, which increases insulin resistance and is associated with type 2 diabetes (18)
Monounsaturates and Heart health
There is epidemiological evidence that dietary MUFAs have a beneficial effect on the risk of CHD. Moreover, evidence from controlled clinical studies has shown that MUFAs favourably affect a number of risk factors for CHD, including plasma lipids and lipoproteins, factors related to thrombogenesis, in vitro LDL oxidative susceptibility and insulin sensitivity.(19)(20)(21)